Description

Hemoglobin J Pointoise is a specific variant of hemoglobin, a crucial oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for advanced research and diagnostic applications where precise molecular characterization is required. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biopharmaceutical companies developing hematological studies and calibrants.

Application

• Biochemical Research: Used as a standard or subject in studies of hemoglobinopathy, oxygen-binding kinetics, and protein structure-function relationships.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material or reference standard in the production of clinical diagnostic kits for detecting hemoglobin variants.
• Hematology Calibrants & Controls: Employed in the formulation of quality control materials and calibrators for hematology analyzers to ensure accurate instrument performance.
• Pharmaceutical Development: Investigated in preclinical research for potential therapeutic applications related to oxygen delivery and blood substitutes.
• Educational & Reference Material: Supplied to academic and teaching laboratories for advanced coursework in biochemistry, physiology, and medical technology.

Basic Information

Product Name	Hemoglobin J Pointoise
CAS No.	62862-90-2
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb J-Pontoise; Hemoglobin J-Pontoise; Hemoglobin variant J Pointoise; α-2 59(E8)Gly->Asp β-2; Hemoglobin α259Gly→Aspβ2; Unstable hemoglobin J Pointoise; HBA2: c.179G>A
EINECS	Contact for details

Quality Control

Our Hemoglobin J Pointoise is produced and handled under strict quality management protocols. Each batch is characterized for identity, purity, and stability to ensure it meets the exacting requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as purity (by HPLC), spectral properties, and physical state is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider lyophilized forms or storage under inert atmosphere. Keep container tightly sealed in a dry and cool environment.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95% (Hb J Pointoise variant)
Assay (Spectrophotometric)	≥ 90% of theoretical heme content
Solubility	Soluble in buffer or aqueous solutions
pH (in solution)	6.5 - 7.5
Endotoxin	< 1.0 EU/mg (for applicable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.