Description

Sodium Butyrate-1-13C is a stable isotope-labeled derivative of sodium butyrate, where the carbon atom at the 1-position is enriched with the 13C isotope. This precise labeling makes it an indispensable internal standard and tracer for advanced analytical and metabolic research, ensuring unparalleled accuracy in quantitative mass spectrometry. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, nutraceutical, and life science sectors for applications demanding exact quantification and metabolic pathway elucidation.

Application

• Quantitative Mass Spectrometry (MS) & LC-MS/MS: Serves as a critical internal standard for the accurate quantification of butyrate and related short-chain fatty acids in complex biological matrices like plasma, serum, and fecal samples.
• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study the dynamics of butyrate metabolism, absorption, and utilization in cell cultures, tissues, and in vivo models.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of sodium butyrate drug candidates in preclinical and clinical research to determine absorption, distribution, metabolism, and excretion (ADME) profiles.
• Nutritional and Gut Microbiome Research: Employed to investigate the role of butyrate as a postbiotic, its production by gut microbiota, and its impact on host health, including immune modulation and epithelial integrity.
• Diagnostic Assay Development: Essential for calibrating and validating high-sensitivity clinical diagnostic tests that measure butyrate levels as a biomarker for gastrointestinal and metabolic disorders.
• Stable Isotope Dilution Assays (SIDA): The gold-standard method for achieving high accuracy and precision in the analysis of butyrate in food, dietary supplements, and pharmaceutical formulations.

Basic Information

Product Name	Sodium Butyrate-1-13C
CAS No.	62601-04-1
Molecular Formula	C313CH7NaO2
Molecular Weight	112.08 g/mol (for 13C1 isotopologue)
Synonyms	Sodium [1-13C]butyrate; Butanoic-1-13C acid, sodium salt; 13C-Labeled Sodium Butyrate; [1-13C]Butyric acid sodium salt; Sodium n-butyrate-1-13C; 1-13C-Sodium Butyrate; NaB-1-13C; Stable Isotope of Sodium Butyrate
EINECS	Contact for details

Quality Control

Every batch of Sodium Butyrate-1-13C CAS NO 62601-04-1 is manufactured and analyzed under strict quality systems. We guarantee high chemical purity and isotopic enrichment, typically ≥98% chemical purity and ≥99 atom % 13C, verified by advanced techniques including NMR and HPLC-MS. Certificates of Analysis (COA) are provided with each shipment, detailing purity, isotopic enrichment, and analytical results. Our quality commitment ensures consistency and reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (Titration)	≥ 98.0% (as Sodium Butyrate)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.