Description

n-Butyric Acid-Carboxy-14C Sodium Salt is a carbon-14 labeled derivative of sodium butyrate, a critical compound for advanced research and development. This radiolabeled analog is essential for precise metabolic and pharmacokinetic studies, enabling detailed tracking of biochemical pathways. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and life science sectors for tracer applications, drug metabolism and disposition (DMD) studies, and analytical method development.

Application

• Tracer Studies in Metabolism Research: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of butyrate and related compounds in biological systems.
• Pharmaceutical Development: Critical for conducting mass balance studies and identifying metabolites during the preclinical and clinical development of new drug candidates.
• Biochemical Pathway Analysis: Enables the elucidation of specific metabolic pathways involving short-chain fatty acids in microbiological, plant, or animal studies.
• Analytical Method Validation: Serves as an internal standard or reference material in advanced analytical techniques such as Liquid Chromatography-Mass Spectrometry (LC-MS) and accelerator mass spectrometry (AMS).
• Agrochemical Research: Applied in environmental fate studies to track the degradation and movement of agrochemicals derived from or related to butyric acid structures.
• Nutritional Science Investigations: Used to study the role of butyrate, a key gut microbiota metabolite, in colonic health and systemic physiology.

Basic Information

Product Name	n-Butyric Acid-Carboxy-14C Sodium Salt
CAS No.	62327-34-8
Molecular Formula	C4H714COONa
Molecular Weight	~112.09 g/mol (for 14C labeled form)
Synonyms	Butanoic-1-14C Acid Sodium Salt; Sodium Butyrate-1-14C; Sodium [1-14C]Butyrate; [1-14C]Butyric Acid Sodium Salt; n-Butyric-1-14C Acid Sodium Salt; Butyric-1-14C Acid Sodium Salt; Sodium n-Butyrate-1-14C; [carboxy-14C]Butyric Acid Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of n-Butyric Acid-Carboxy-14C Sodium Salt is manufactured and controlled under a strict quality management system. The product undergoes comprehensive analytical testing to ensure identity, purity, and specific activity meet the stringent requirements for research use. Certificates of Analysis (COA) detailing radiopurity (by HPLC), specific activity, chemical purity, and solvent content are provided with each shipment to guarantee traceability and consistency for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Handle and dispose of in accordance with all applicable local, national, and international radiation safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (Residual)	Meets internal specifications

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.