Description

(R)-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Ethan-1-One is a high-value chiral building block and intermediate, specifically the (R)-enantiomer of a protected form of hydroxyacetone. Its core value proposition lies in its role as a versatile synthon for the stereoselective synthesis of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials where precise stereochemistry is critical for biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of various drug candidates, including antiviral agents, antibiotics, and cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or building block in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Natural Product Synthesis: Employed in the total synthesis of natural products that contain chiral hydroxyketone or diol motifs.
• Agrochemical Research: Serves as an intermediate in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Flavor and Fragrance Industry: Potential use in the synthesis of chiral aroma chemicals and flavoring agents.
• Material Science: Can be utilized in the preparation of chiral ligands for catalysis or as a monomer for specialized polymers.

Basic Information

Product Name	(R)-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Ethan-1-One
CAS No.	61821-86-1
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(R)-1-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethanone; (R)-4-Acetyl-2,2-dimethyl-1,3-dioxolane; (R)-(-)-1-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethan-1-one; (R)-(-)-4-Acetyl-2,2-dimethyl-1,3-dioxolane; (R)-Acetonylacetone cyclic ketal; (R)-Hydroxyacetone cyclic ketal; (R)-1-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethanone; (4R)-2,2-Dimethyl-4-acetyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our (R)-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Ethan-1-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.