Description

Cyclohexylbis[5-Methyl-2-(1-Methylethyl)Cyclohexyl]Phosphine is a specialized organophosphorus ligand with a sterically demanding, electron-rich structure. This compound is valued for its ability to modulate the activity and selectivity of transition metal catalysts in critical synthetic transformations. It is primarily sought by research institutions and industrial R&D departments engaged in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals.

Application

• As a ligand in homogeneous catalysis for cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
• To enhance catalyst selectivity and efficiency in asymmetric hydrogenation and hydroformylation processes.
• In academic and industrial research for developing novel catalytic systems for C-C and C-X bond formation.
• For the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and agrochemical intermediates.
• As a key component in catalyst screening kits for high-throughput experimentation in drug discovery.

Basic Information

Product Name	Cyclohexylbis[5-Methyl-2-(1-Methylethyl)Cyclohexyl]Phosphine
CAS No.	61142-16-3
Molecular Formula	C31H55P
Molecular Weight	458.75 g/mol
Synonyms	Cyclohexylbis(5-methyl-2-(1-methylethyl)cyclohexyl)phosphine; (Cyclohexyl)bis[5-methyl-2-(propan-2-yl)cyclohexyl]phosphane; Tris(alkyl)phosphine ligand; Bulky trialkylphosphine; Sterically hindered phosphine ligand; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of Cyclohexylbis[5-Methyl-2-(1-Methylethyl)Cyclohexyl]Phosphine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by NMR (1H, 13C, 31P) and HPLC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, containers should be purged with inert gas after each opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.