Description

2,3,4-Trifluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block essential for advanced organic synthesis. This compound is valued for its trifluoromethyl-substituted benzene ring, which imparts unique electronic and steric properties critical for modifying the pharmacokinetic profiles of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where fluorination is a common strategy to improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules used in display technologies.
• Polymer Modification: Incorporated into polymer chains to create specialty polymers with enhanced chemical resistance, thermal stability, or specific surface properties.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Sonogashira) and as a precursor for acid chlorides, esters, and amides in complex molecule construction.
• Chemical Research & Development: A valuable standard and reagent in academic and industrial R&D labs exploring fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	2,3,4-Trifluorobenzoic Acid
CAS No.	61079-72-9
Molecular Formula	C7H3F3O2
Molecular Weight	176.09 g/mol
Synonyms	Benzoic acid, 2,3,4-trifluoro-; 2,3,4-Trifluorobenzenecarboxylic acid; 2,3,4-Trifluorophenylcarboxylic acid; 2,3,4-TFBA; α,α,α-Trifluoro-o-veratric acid (obsolete); 2,3,4-Trifluoro-benzoic acid
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.