Description

Amrinone is a bipyridine derivative and a potent phosphodiesterase III inhibitor, primarily recognized for its inotropic and vasodilatory effects. This compound is of significant interest in pharmaceutical research and development, particularly for its role in the study of cardiac function and hemodynamics. It serves as a critical active pharmaceutical ingredient (API) and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical API: Used as the active ingredient in the formulation of cardiac stimulant medications.
• Biochemical Research: Employed as a key tool compound in cardiovascular research to study phosphodiesterase inhibition and myocardial contractility.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Preclinical Studies: Utilized in animal models to investigate therapeutic effects on heart failure and related conditions.
• Process Development: Acts as an intermediate or target molecule in the development and optimization of synthetic routes within process chemistry.

Basic Information

Product Name	Amrinone
CAS No.	60719-84-8
Molecular Formula	C10H9N3O
Molecular Weight	187.20 g/mol
Synonyms	5-Amino-3,4'-bipyridine-6(1H)-one; Inamrinone; 5-Amino-3,4'-bipyridin-6-one; WIN 40680; 3,4'-Bipyridin-6(1H)-one, 5-amino-; 5-Amino-1,6-dihydro-3,4'-bipyridin-6-one; 5-Amino-1,6-dihydro-6-oxo-3,4'-bipyridine
EINECS	Contact for details

Quality Control

Our Amrinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.