Description

n-Methylhomatropinium Nitrate is a quaternary ammonium salt derivative of homatropine, primarily utilized as a pharmacological reference standard and research chemical. This compound is valued for its high purity and stability, which are critical for ensuring the accuracy and reproducibility of experimental and analytical results. It is essential for pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions conducting studies in neuropharmacology and receptor characterization.

Application

• Pharmacological Research: Acts as a muscarinic acetylcholine receptor (mAChR) antagonist for in vitro and ex vivo studies.
• Analytical Reference Standard: Used as a high-purity calibrant in HPLC, LC-MS, and other chromatographic methods for method development and validation.
• Biochemical Assay Development: Serves as a key ligand in competitive binding assays to screen and characterize new therapeutic compounds.
• Academic & Educational Use: Employed in university laboratories for teaching advanced concepts in medicinal chemistry and neuropharmacology.
• Pharmaceutical Quality Control: Utilized as a system suitability standard in the analysis of related substances and impurities.

Basic Information

Product Name	n-Methylhomatropinium Nitrate
CAS No.	60539-03-9
Molecular Formula	C17H24N2O3 • HNO3
Molecular Weight	367.40 g/mol
Synonyms	N-Methylhomatropinium Nitrate; Homatropine Methylnitrate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2-phenylacetate methyl nitrate; Tropine 2-Hydroxy-2-phenylacetate Methyl Nitrate; Methylhomatropinium Nitrate
EINECS	Contact for details

Quality Control

Our n-Methylhomatropinium Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and analytical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.