Description

Gonyautoxiniii CAS NO 60537-65-7 is a potent neurotoxin belonging to the saxitoxin family, a class of compounds known for their specific action on voltage-gated sodium channels. This high-purity reference standard is critical for analytical research, toxicological studies, and the development of detection methods for marine biotoxins. It is an essential material for researchers and quality control laboratories in the fields of marine biology, food safety, and pharmaceutical development who require reliable and well-characterized compounds for their work.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the calibration and validation of analytical methods such as HPLC, LC-MS/MS, and receptor binding assays in shellfish toxin monitoring programs.
• Toxicological Research: Fundamental tool for studying the mechanism of action of paralytic shellfish poisoning (PSP) toxins, including ion channel blockade kinetics and structure-activity relationships.
• Diagnostic Development: Key component in the development and quality control of rapid test kits, biosensors, and immunoassays for the detection of saxitoxin analogues in environmental and food samples.
• Pharmaceutical Research: Used in neuroscience research to investigate sodium channel function and in the discovery of potential therapeutic agents or antidotes for neurotoxin exposure.
• Regulatory Compliance & Food Safety: Enables accurate quantification of Gonyautoxin-III in seafood to ensure compliance with international regulatory limits set by bodies like the FDA, EFSA, and Codex Alimentarius.

Basic Information

Item	Detail
Product Name	Gonyautoxiniii
CAS No.	60537-65-7
Molecular Formula	C10H17N7O6
Molecular Weight	315.28 g/mol
Synonyms	Gonyautoxin III; GTX3; 11-Hydroxysaxitoxin sulfate; 11α-Hydroxysaxitoxin sulfate ester; Paralytic Shellfish Poison GTX3; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,10H-pyrrolo(1,2-c)purine-9,10-dione 9-sulfate; Saxitoxin derivative GTX3
EINECS	Contact for details

Quality Control

Our Gonyautoxiniii is produced and handled under strict quality protocols to ensure identity, purity, and stability. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced chromatographic and spectroscopic analyses. We adhere to ISO 17034 principles for reference material production, and our quality systems support traceability and reliability for critical research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0 % w/w
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.