Description

Gonyautoxin Ii CAS NO 60508-89-6 is a potent neurotoxin belonging to the saxitoxin family, a class of naturally occurring compounds known for their high biological activity. This specific congener is critical for advanced research in neuropharmacology and toxicology, where precise molecular tools are required. It is primarily utilized by research institutions, pharmaceutical developers, and specialized diagnostic laboratories for receptor binding studies, channel blocking assays, and the development of detection methods for marine biotoxins.

Application

• Neuroscience Research: As a highly selective sodium channel blocker for studying neuronal signal transduction and action potential mechanisms.
• Pharmacological Studies: Used in the characterization and development of novel analgesics and anesthetics that target voltage-gated sodium channels.
• Toxicology & Risk Assessment: Serves as a reference standard in the analysis of shellfish and marine samples for paralytic shellfish poisoning (PSP) toxins.
• Diagnostic Development: Essential for the calibration and validation of analytical methods such as HPLC, LC-MS/MS, and receptor binding assays for biotoxin monitoring.
• Biomedical Tool Compound: Employed in electrophysiology experiments to investigate channel function and in the study of neuromuscular disorders.

Basic Information

Product Name	Gonyautoxin Ii
CAS No.	60508-89-6
Molecular Formula	C10H17N7O6
Molecular Weight	331.29 g/mol
Synonyms	GTX2; Gonyautoxin-2; 11α-Hydroxysaxitoxin; 11-Hydroxysaxitoxin; 11-Hydroxy-STX; Saxitoxin 11-α-ol; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,10H-pyrrolo(1,2-c)purine-9,9,10-triol
EINECS	Contact for details

Quality Control

Our Gonyautoxin Ii is produced and handled under strict quality protocols suitable for research applications. Each batch is characterized using advanced analytical techniques to ensure identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles via HPLC and/or LC-MS/MS is provided with every shipment to guarantee reproducibility and traceability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Assay (HPLC)	≥ 90% (by weight against certified reference standard)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.