Description

Ent- Galanthamine CAS NO 60384-53-4 is the enantiomer of the naturally occurring alkaloid galanthamine, serving as a critical chiral building block and reference standard in advanced pharmaceutical research and development. This compound is of significant value for studying stereoselective biological activity and for the synthesis of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on neurology, aging-related diseases, and chiral chemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity chiral standard for analytical method development, validation, and quality control in API manufacturing.
• Chiral Intermediate: Serves as a key starting material or intermediate in the enantioselective synthesis of potential galanthamine analogs and other complex molecules.
• Biochemical Research: Employed in in vitro studies to investigate the structure-activity relationship (SAR) and the specific effects of the ent-enantiomer on biological targets, such as acetylcholinesterase.
• Academic Research: Utilized in university and institutional labs for studies in organic chemistry, medicinal chemistry, and neuropharmacology.
• Process Development & Scale-up: Acts as a benchmark compound for developing and optimizing synthetic routes in pilot plants and kilo labs.

Basic Information

Product Name	Ent- Galanthamine
CAS No.	60384-53-4
Molecular Formula	C17H21NO3
Molecular Weight	287.35 g/mol
Synonyms	(-)-Galanthamine; (1S,12S,13S)-13-Methyl-11-azahexacyclo[7.7.1.02,7.03,6.09,14.013,17]heptadeca-2,4,6,9(14)-tetraen-12-ol; Ent-Galanthamine; Galanthamine Enantiomer; (1S,12S,13S)-3-Methoxy-17-methyl-11-azahexacyclo[7.7.1.02,7.03,6.09,14.013,17]heptadeca-2,4,6,9(14)-tetraen-12-ol
EINECS	Contact for details

Quality Control

Our Ent- Galanthamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.