Description

Atropine Hydrobromide is a high-purity, crystalline salt form of the classic anticholinergic alkaloid atropine. This compound is essential for its potent and reliable pharmacological activity as a muscarinic antagonist, offering critical control over parasympathetic nervous system responses. It is a fundamental active pharmaceutical ingredient (API) and research chemical for manufacturers and laboratories in the pharmaceutical, ophthalmic, and life science sectors globally.

Application

• Pharmaceutical API: Core ingredient in the formulation of injectable solutions, ophthalmic drops, and pre-operative medications for its anticholinergic and mydriatic effects.
• Ophthalmic Solutions: Used to dilate pupils (mydriasis) and paralyze accommodation (cycloplegia) for eye examinations and surgical procedures.
• Antidote Production: Critical component in antidotes for organophosphate and carbamate pesticide or nerve agent poisoning.
• Research & Development: A standard reference compound in pharmacological studies targeting muscarinic acetylcholine receptors and autonomic nervous system function.
• Veterinary Medicine: Employed in veterinary practices for similar diagnostic and therapeutic purposes as in human medicine.
• Analytical Standards: Serves as a certified reference material (CRM) for quality control and assay calibration in pharmaceutical analysis.

Basic Information

Product Name	Atropine Hydrobromide
CAS No.	6415-90-3
Molecular Formula	C17H23NO3·HBr
Molecular Weight	384.28 g/mol
Synonyms	Atropine HBr; Atropine Hydrobromide Salt; dl-Hyoscyamine Hydrobromide; Tropine Tropate Hydrobromide; (±)-Hyoscyamine Hydrobromide; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate hydrobromide; Endopos; Atropinol.
EINECS	229-148-7

Quality Control

Our Atropine Hydrobromide is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided for every shipment, detailing results for identity, assay, purity, and related substances to ensure supply reliability and regulatory compliance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (Titration)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Specific Rotation	-0.10° to +0.10° (c = 5 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.