Description

Pht-Gly-Otbu CAS NO 6297-93-4 is a protected amino acid derivative, specifically the tert-butyl ester of phthaloylglycine, widely used as a key synthetic intermediate in organic chemistry. This compound is valued for its role in facilitating peptide coupling and protecting group strategies, enabling the efficient synthesis of complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides.
• Peptide Chemistry: Serves as a protected glycine derivative in solid-phase and solution-phase peptide synthesis.
• Organic Synthesis: Acts as a versatile intermediate for introducing glycine moieties in complex organic molecules.
• Bioconjugation: Employed in the development of linker molecules and probes for bioconjugation applications.
• Academic & Industrial R&D: A standard reagent in research laboratories for method development and exploratory chemistry.

Basic Information

Product Name	Pht-Gly-Otbu
CAS No.	6297-93-4
Molecular Formula	C₁₄H₁₅NO₄
Molecular Weight	261.27 g/mol
Synonyms	N-Phthaloylglycine tert-Butyl Ester; tert-Butyl 2-(1,3-Dioxoisoindolin-2-yl)acetate; Phthalimidoglycine tert-Butyl Ester; 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic Acid tert-Butyl Ester; Glycine, N-phthaloyl-, 1,1-dimethylethyl ester; Pht-Gly-OtBu; Pht-Gly-Ot-Bu; N-(tert-Butoxycarbonylmethyl)phthalimide
EINECS	Contact for details

Quality Control

Our Pht-Gly-Otbu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.