Description

(+)-Diacetyl-L-Tartaric Anhydride is a high-purity chiral building block and resolving agent, essential for the synthesis of enantiomerically pure compounds. Its primary value lies in its ability to form diastereomeric salts for the optical resolution of racemic mixtures, particularly amines and amino acids. This makes it a critical material for pharmaceutical manufacturers, fine chemical producers, and research institutions focused on developing chiral active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Resolution Agent: Key for the optical purification of racemic amines, amino alcohols, and other basic pharmaceuticals.
• Pharmaceutical Intermediate: Used in the synthesis of enantiomerically pure drugs, including certain antibiotics and cardiovascular agents.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor to catalysts in stereoselective chemical reactions.
• Food Additive Precursor: Intermediate in the production of food-grade emulsifiers like diacetyl tartaric acid esters of mono- and diglycerides (DATEM).
• Analytical Chemistry: Employed as a derivatizing agent for chiral analysis via chromatography (HPLC, GC).
• Polymer Modification: Used to introduce chiral centers or functional groups into specialty polymers.

Basic Information

Product Name	(+)-Diacetyl-L-Tartaric Anhydride
CAS No.	6283-74-5
Molecular Formula	C8H8O7
Molecular Weight	216.15 g/mol
Synonyms	DAT Anhydride; (2R,3R)-2,3-Diacetoxysuccinic Anhydride; L-(+)-Diacetyl Tartaric Anhydride; (3R,4R)-3,4-Diacetoxy-2,5-dihydrofuran-2,5-dione; Anhydride of L-(+)-Diacetyl Tartaric Acid; (R,R)-Diacetyl Tartaric Anhydride; Acetylated Tartaric Acid Anhydride; EINECS 228-500-1
EINECS	228-500-1

Quality Control

Our (+)-Diacetyl-L-Tartaric Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical assay, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to prevent hydrolysis. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	+135° to +145° (c=1 in acetone)
Melting Point	128°C - 132°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.