Description

3,6-Difluorophthalic Anhydride is a high-purity fluorinated aromatic anhydride, a critical building block for advanced material synthesis. Its value lies in the introduction of fluorine atoms and reactive anhydride functionality, enabling precise tuning of polymer properties and facilitating downstream chemical modifications. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel, high-performance products.

Application

• Pharmaceutical Intermediates: A key precursor in synthesizing active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to manufacture advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Polyimide & High-Performance Polymers: Serves as a monomer for producing fluorinated polyimides, which exhibit exceptional thermal stability, low dielectric constant, and optical clarity for electronics and aerospace applications.
• Liquid Crystal Materials: Employed in the synthesis of fluorinated liquid crystal compounds for advanced display technologies.
• Dye & Pigment Intermediates: Acts as a building block for creating specialized fluorinated dyes and pigments with unique color fastness and properties.
• Epoxy Curing Agents & Modifiers: Imparts improved chemical resistance and thermal properties to epoxy resin systems.
• Organic Synthesis Reagent: Utilized in academic and industrial research labs for constructing complex fluorinated aromatic structures.

Basic Information

Product Name	3,6-Difluorophthalic Anhydride
CAS No.	652-40-4
Molecular Formula	C8H2F2O3
Molecular Weight	184.10 g/mol
Synonyms	3,6-Difluorophthalic anhydride; 3,6-Difluoroisobenzofuran-1,3-dione; 4,5-Difluorophthalic Anhydride; 1,3-Isobenzofurandione, 4,5-difluoro-; Difluorophthalic Anhydride; 4,5-Difluorobenzene-1,2-dicarboxylic Anhydride; 652-40-4 (CAS); DFPA
EINECS	211-476-5

Quality Control

Our 3,6-Difluorophthalic Anhydride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for high-value synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.