Description

2,3,5,6-Tetrafluoro-4-Methylbenzoic Acid is a highly fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique perfluorinated aromatic structure provides exceptional stability and lipophilicity, making it invaluable for creating novel compounds with tailored properties. This intermediate is primarily sought by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by material scientists for specialty polymers and liquid crystal applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with enhanced environmental stability and efficacy.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer Modification: Incorporated into specialty polymers, such as polyimides and polyesters, to improve chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Serves as a component in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and creating novel aromatic compounds.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Methylbenzoic Acid
CAS No.	652-32-4
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	4-Methyl-2,3,5,6-tetrafluorobenzoic Acid; 2,3,5,6-Tetrafluoro-p-toluic Acid; Tetrafluoromethylbenzoic Acid; Benzoic acid, 2,3,5,6-tetrafluoro-4-methyl-; α,α,α,α-Tetrafluoro-4-methylbenzoic Acid; 4-(Trifluoromethyl)-2,3,5,6-tetrafluorobenzoic Acid (related isomer); TFMBA (abbrev.)
EINECS	Contact for details

Quality Control

Our production of 2,3,5,6-Tetrafluoro-4-Methylbenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.