Description

Allocolchicine is a structurally significant alkaloid derivative, closely related to the natural product colchicine, known for its potent biological activity. This compound serves as a crucial intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel colchicine analogs and other bioactive molecules for drug discovery programs.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating tubulin polymerization inhibition and cytoskeleton dynamics.
• Academic Research: Employed in medicinal chemistry and pharmacology laboratories for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for the custom synthesis of specialized compounds for clinical and pre-clinical testing.

Basic Information

Product Name	Allocolchicine
CAS No.	641-28-1
Molecular Formula	C21H23NO5
Molecular Weight	369.41 g/mol
Synonyms	N-Acetylcolchinol; Colchinol Methyl Ether; 7-Acetamido-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one; Allocolchicine; NSC 406042; (-)-Allocolchicine; (S)-Allocolchicine
EINECS	211-382-8

Quality Control

Our Allocolchicine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.