Description

(-)-(3Ar,6Ar)-Tetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-One is a high-purity chiral building block and protected lactone derivative essential for advanced organic synthesis. Its defined stereochemistry and functional group make it a critical intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate in catalytic asymmetric reactions to introduce stereocenters.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Building block for creating specialty chemicals, flavors, fragrances, and advanced material precursors.
• Academic & Industrial R&D: Valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(-)-(3Ar,6Ar)-Tetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-One
CAS No.	595581-64-9
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(-)-2,2-Dimethyl-1,3-dioxolane-4-acetic acid γ-lactone; (3aR,6aR)-Tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-one; (R,R)-Tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-one; (-)-Dimethyl Dioxolane Lactone; Chiral Dioxolane Lactone; (3aR,6aR)-Hexahydro-2,2-dimethyl-4H-cyclopenta[d][1,3]dioxol-4-one; Protected (R)-4-Hydroxypentanoic Acid Lactone Derivative
EINECS	Contact for details

Quality Control

Our production of (-)-(3Ar,6Ar)-Tetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-One adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques including chiral HPLC, GC, and NMR to verify identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.