Description

Methyl 2-Fluoro-3-Methylbenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methyl substituents on the benzoate core, which allows for precise modulation of electronic and steric properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Fluorine Chemistry Research: A valuable reference standard and building block for studying structure-activity relationships (SAR) in fluorinated compounds.

Basic Information

Product Name	Methyl 2-Fluoro-3-Methylbenzoate
CAS No.	586374-04-1
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	2-Fluoro-3-methylbenzoic acid methyl ester; Methyl 2-fluoro-m-toluate; Benzoic acid, 2-fluoro-3-methyl-, methyl ester; 3-Methyl-2-fluorobenzoic acid methyl ester; 2-Fluoro-3-methyl methylbenzoate; Methyl 3-methyl-2-fluorobenzoate; m-Toluic acid, 2-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.