Description

(R)-DTBM-SEGPHOS is a highly effective chiral bisphosphine ligand widely used in asymmetric catalysis. Its value lies in enabling the production of enantiomerically pure compounds, which are critical for pharmaceuticals and advanced materials. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high stereoselectivity in hydrogenation and cross-coupling reactions.

Application

• Asymmetric hydrogenation of olefins, ketones, and imines for pharmaceutical intermediate synthesis.
• Catalytic asymmetric cross-coupling reactions to form carbon-carbon bonds.
• Production of chiral active pharmaceutical ingredients (APIs) and agrochemicals.
• Key ligand in rhodium and ruthenium-catalyzed processes for high enantiomeric excess.
• Research and development of novel catalytic systems in academic and industrial laboratories.
• Manufacture of specialty chemicals and advanced materials requiring specific chirality.

Basic Information

Product Name	(R)-DTBM-SEGPHOS
CAS No.	566940-03-2
Molecular Formula	C46H64O2P2
Molecular Weight	710.93 g/mol
Synonyms	(R)-5,5'-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole; (R)-DTBM-SEGPHOS; (R)-2,2'-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (R)-SEGPHOS derivative; (R)-DTBM-SEGPHOS ligand; (R)-Bisphosphine ligand DTBM-SEGPHOS; (R)-DTBM-SEGPHOS, min. 97%
EINECS	Contact for details

Quality Control

Our (R)-DTBM-SEGPHOS is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analysis, including chiral purity verification by HPLC and 31P NMR spectroscopy. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the container should be kept sealed to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.