Description

[3-(4-Fluorophenyl)-2-Oxochromen-7-Yl] Acetate is a high-purity fluorinated coumarin derivative, a key advanced intermediate in organic synthesis. This compound matters for its precise molecular architecture, which serves as a critical building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Fluorescent Probe Synthesis: Serves as a core structure for creating specialized coumarin-based fluorescent dyes and sensors used in bioimaging and diagnostics.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or emissive layer materials in advanced display technologies.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in fluorination and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	[3-(4-Fluorophenyl)-2-Oxochromen-7-Yl] Acetate
CAS No.	549501-16-8
Molecular Formula	C₁₇H₁₁FO₄
Molecular Weight	298.27 g/mol
Synonyms	7-Acetoxy-3-(4-fluorophenyl)-2H-chromen-2-one; 3-(4-Fluorophenyl)-2-oxo-2H-chromen-7-yl acetate; 7-Acetyloxy-3-(4-fluorophenyl)coumarin; 3-(p-Fluorophenyl)-7-acetoxycoumarin; 7-Acetoxy-3-(4'-fluorophenyl)coumarin; 2-Oxo-3-(4-fluorophenyl)-2H-chromen-7-yl acetate; 549501-16-8; 3-(4-Fluorophenyl)-7-hydroxycoumarin acetate
EINECS	Contact for details

Quality Control

Our [3-(4-Fluorophenyl)-2-Oxochromen-7-Yl] Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP-grade requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flame, and incompatible materials. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.