Description

Hiv-1 Integrase Inhibitor CAS NO 544467-07-4 is a high-purity, small molecule pharmaceutical intermediate designed for research and development. This compound is critical for the synthesis of novel antiretroviral agents targeting the HIV-1 integrase enzyme, a key mechanism in viral replication. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in antiviral drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced HIV-1 integrase strand transfer inhibitors (INSTIs).
• Antiviral Drug Discovery: Core scaffold for medicinal chemistry optimization and structure-activity relationship (SAR) studies.
• Biochemical Research: Used as a reference standard or active compound in enzymatic assays targeting HIV-1 integrase.
• Preclinical Development: Serves as a starting material for producing compounds for in vitro and in vivo efficacy and toxicity studies.
• Academic Research: Facilitates fundamental virology and pharmacology research into HIV replication mechanisms and inhibition.

Basic Information

Product Name	Hiv-1 Integrase Inhibitor
CAS No.	544467-07-4
Molecular Formula	C₂₀H₁₉F₃N₄O₆
Molecular Weight	468.39 g/mol
Synonyms	Bictegravir Intermediate; GS-9883 Intermediate; (2R,5S,13aR)-8-Hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid, 6-fluoro-1-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one derivative; HIV Integrase Inhibitor Precursor; INSTI Intermediate; Antiretroviral API Intermediate
EINECS	Contact for details

Quality Control

Our Hiv-1 Integrase Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.