Description

4-Benzyloxy-3-Trifluoromethylbenzoic Acid is a high-purity, synthetically valuable aromatic carboxylic acid derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce trifluoromethyl and benzyloxy functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials for displays and organic light-emitting diodes.
• Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research (R&D): Versatile reagent in medicinal chemistry and process development for structure-activity relationship (SAR) studies.
• Complex Ligand Synthesis: Intermediate for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Benzyloxy-3-Trifluoromethylbenzoic Acid
CAS No.	536975-35-6
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	3-(Trifluoromethyl)-4-(phenylmethoxy)benzoic Acid; 4-(Benzyloxy)-3-(trifluoromethyl)benzoic Acid; Benzoic acid, 4-(benzyloxy)-3-(trifluoromethyl)-; 4-(Phenylmethoxy)-3-(trifluoromethyl)benzoic Acid; 4-O-Benzyl-3-trifluoromethylbenzoic Acid; 3-Trifluoromethyl-4-benzyloxybenzoic Acid; BTFBA (abbreviation); α,α,α-Trifluoro-4-benzyloxy-m-toluic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-3-Trifluoromethylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.