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6-Bromo-2,3,4-Trifluorobenzoic Acid CAS NO 530145-53-0
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CAS No.:530145-53-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Bromo-2,3,4-Trifluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique combination of bromine and fluorine substituents makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and specialty materials.
Application
- Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for fluorine-containing drugs targeting CNS disorders, anti-infectives, and oncology.
- Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
- Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
- Polymer Modification: Employed to introduce fluorine and bromine functional groups into polymer backbones, altering properties like chemical resistance, thermal stability, and solubility.
- Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
- Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science labs for structure-activity relationship (SAR) studies and novel compound library synthesis.
Basic Information
| Item | Details |
|---|---|
| Product Name | 6-Bromo-2,3,4-Trifluorobenzoic Acid |
| CAS No. | 530145-53-0 |
| Molecular Formula | C7H2BrF3O2 |
| Molecular Weight | 260.99 g/mol |
| Synonyms | 2,3,4-Trifluoro-6-bromobenzoic Acid; 6-Bromo-2,3,4-trifluorobenzoic Acid; Benzoic acid, 6-bromo-2,3,4-trifluoro-; 6-Bromo-2,3,4-trifluorobenzoic acid (CAS 530145-53-0); 2,3,4-Trifluoro-6-bromobenzoic acid; 6-Br-2,3,4-F3-BA |
| EINECS | Contact for details |
Quality Control
Our 6-Bromo-2,3,4-Trifluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under ISO and cGMP guidelines.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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