Description

(1R,1'R,2S,2'S)-Duanphos is a highly valuable chiral bisphosphine ligand widely recognized for its exceptional performance in asymmetric catalysis. Its primary value lies in enabling the synthesis of enantiomerically pure compounds, which are critical for the development of pharmaceuticals and advanced materials. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high selectivity and yield in transition-metal-catalyzed reactions such as hydrogenation and cross-coupling.

Application

• Asymmetric hydrogenation of olefins, ketones, and imines for pharmaceutical intermediate synthesis.
• Catalytic asymmetric carbon-carbon bond formation reactions, including cross-couplings.
• Key ligand in the synthesis of chiral active pharmaceutical ingredients (APIs).
• Production of enantiomerically enriched agrochemicals and flavors/fragrances.
• Academic and industrial research in developing new catalytic methodologies.
• Process development and scale-up for commercial manufacturing of chiral compounds.

Basic Information

Product Name	(1R,1'R,2S,2'S)-Duanphos
CAS No.	528814-26-8
Molecular Formula	C26H24P2
Molecular Weight	398.41 g/mol
Synonyms	(1R,1'R,2S,2'S)-(-)-1,1'-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene; DuanPhos; (S,S)-DuanPhos; (-)-Duanphos; (1R,1'R,2S,2'S)-1,1'-Bis[(2S,5S)-2,5-dimethylphospholanyl]ferrocene; (S,S)-1,1'-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene; (1R,1'R,2S,2'S)-1,1'-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene
EINECS	Contact for details

Quality Control

Our (1R,1'R,2S,2'S)-Duanphos is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess, meeting the rigorous demands of process chemistry and API synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity confirmation. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Moisture (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.