Description

Sodium 3,4-Difluorobenzoate is the sodium salt derivative of 3,4-difluorobenzoic acid, a key fluorinated aromatic building block. This compound is valued for its enhanced solubility and stability, making it a versatile intermediate in advanced synthetic chemistry. It is primarily utilized by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to enhanced activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer & Material Science: Acts as a monomer or additive for creating specialty polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis Reagent: Employed in various coupling reactions and as a precursor for other difluorinated aromatic compounds in research and development.

Basic Information

Product Name	Sodium 3,4-Difluorobenzoate
CAS No.	522651-44-1
Molecular Formula	C7H3F2NaO2
Molecular Weight	180.08 g/mol
Synonyms	3,4-Difluorobenzoic Acid Sodium Salt; Benzoic acid, 3,4-difluoro-, sodium salt (1:1); Sodium 3,4-difluorobenzoate; 3,4-Difluorobenzoate sodium; 522651-44-1; Sodium 3,4-difluorobenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Sodium 3,4-Difluorobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents is available for every batch upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.