Description

Sodium 2,5-Difluorobenzoate is an organofluorine compound and the sodium salt of 2,5-difluorobenzoic acid, serving as a versatile and valuable building block in advanced organic synthesis. This high-purity intermediate is critical for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and stability. It is primarily sought by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluoro-substituted aromatic ring enhances product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing benzoate groups into polymer chains, improving material properties like chemical resistance and thermal stability.
• Chemical Research & Development: A fundamental building block in academic and industrial R&D for exploring new fluorination chemistry and creating specialized chemical libraries.

Basic Information

Product Name	Sodium 2,5-Difluorobenzoate
CAS No.	522651-42-9
Molecular Formula	C7H3F2NaO2
Molecular Weight	180.08 g/mol
Synonyms	2,5-Difluorobenzoic Acid Sodium Salt; Benzoic acid, 2,5-difluoro-, sodium salt (1:1); Sodium 2,5-difluorobenzoate; 2,5-Difluorobenzoate Sodium Salt; 2,5-DFBA Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium 2,5-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture from the air, which may affect quality and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.