Description

Vortioxetine CAS NO 508233-74-7 is a high-purity active pharmaceutical ingredient (API) belonging to the class of novel multimodal antidepressants. This compound is critical for the development and manufacturing of advanced pharmaceutical formulations targeting major depressive disorder (MDD). It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in the production of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical API: Primary active ingredient in the commercial manufacture of antidepressant medications.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control and method validation.
• Clinical Research: Serves as a key material in preclinical and clinical studies for new CNS drug development.
• Formulation Development: Utilized in R&D for developing various dosage forms such as tablets and capsules.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent generic versions of branded antidepressants.
• Academic Research: Employed in university and institutional studies investigating serotonin receptor pharmacology.

Basic Information

Product Name	Vortioxetine
CAS No.	508233-74-7
Molecular Formula	C18H22N2S
Molecular Weight	298.45 g/mol
Synonyms	1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine; Lu AA21004; Brintellix; Trintellix; Vortioxetine Hydrobromide; Vortioxetine HBr; Vioxetine
EINECS	Contact for details

Quality Control

Our Vortioxetine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (e.g., USP, EP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 0.5% Any single impurity ≤ 0.1%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.