Description

Benzoyl Chloride, 4-Amino-3-Fluoro- (9Ci) CAS NO 503315-76-2 is a high-purity, multi-functional aromatic building block featuring both an amino group and a reactive acid chloride moiety. This compound is critically important for the synthesis of complex molecules, enabling the introduction of the benzoyl scaffold with specific fluorine and amine substitution patterns. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors, antibiotics, and CNS-active compounds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides with enhanced biological activity and selectivity.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic cores for advanced electronic display and lighting materials.
• Polymer Modification: Serves as a monomer or cross-linking agent for engineering plastics and high-performance polymers.
• Peptide Mimetics & Bioconjugation: Facilitates the acylation of amines in peptides or biomolecules for labeling and structural modification.
• Dye & Pigment Manufacturing: Intermediate for creating specialized fluorinated dyes and colorants with unique properties.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	Benzoyl Chloride, 4-Amino-3-Fluoro- (9Ci)
CAS No.	503315-76-2
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	4-Amino-3-fluorobenzoyl chloride; 3-Fluoro-4-aminobenzoyl chloride; 4-Amino-3-fluorobenzoic acid chloride; 2-Fluoro-4-(chlorocarbonyl)aniline; Benzoic acid, 4-amino-3-fluoro-, chloride; 503315-76-2; 4-Amino-3-fluorobenzoylchloride
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 4-Amino-3-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.