Description

Benzoic Acid, 3-(Acetylamino)-5-(Trifluoromethyl)- is a specialized trifluoromethylated benzoic acid derivative, identified by CAS No. 500590-51-2, that serves as a high-value synthetic intermediate. Its molecular structure, featuring both an acetylamino and a trifluoromethyl group, makes it a critical building block for creating advanced compounds with enhanced properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorine chemistry for improved bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Benzoic Acid, 3-(Acetylamino)-5-(Trifluoromethyl)-
CAS No.	500590-51-2
Molecular Formula	C10H8F3NO3
Molecular Weight	247.17 g/mol
Synonyms	3-Acetamido-5-(trifluoromethyl)benzoic acid; 5-(Trifluoromethyl)-3-acetamidobenzoic acid; N-[3-Carboxy-5-(trifluoromethyl)phenyl]acetamide; 3-Acetylamino-5-trifluoromethylbenzoic acid; 3-(Acetylamino)-5-(trifluoromethyl)benzoic Acid; Benzoic acid, 3-(acetylamino)-5-(trifluoromethyl)-; 500590-51-2
EINECS	Contact for details

Quality Control

Every batch of Benzoic Acid, 3-(Acetylamino)-5-(Trifluoromethyl)- is produced and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.