Description

L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-[(4-Methylphenyl)Amino]-2-Oxoethyl]-, Methyl Ester (9Ci) is a sophisticated chiral organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its value lies in its unique molecular architecture, combining a valine-derived backbone with a diphenylphosphino group and an aromatic amine, making it a versatile ligand precursor and building block for complex molecules. This high-purity specialty chemical is essential for researchers and manufacturers in pharmaceutical development, asymmetric catalysis, and the synthesis of novel materials where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring specific stereochemistry.
• Catalyst Ligand Precursor: Used to synthesize specialized phosphine-based ligands for transition metal catalysis, enabling highly selective asymmetric hydrogenation and cross-coupling reactions.
• Chemical Research & Development: Serves as a valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.
• Agrochemical Synthesis: Employed in the development of advanced, enantiomerically pure agrochemicals, such as herbicides and plant growth regulators.
• Material Science: A potential monomer or additive in the synthesis of specialty polymers and advanced organic materials with tailored properties.

Basic Information

Item	Details
Product Name	L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-[(4-Methylphenyl)Amino]-2-Oxoethyl]-, Methyl Ester (9Ci)
CAS No.	500316-82-5
Molecular Formula	C31H31N2O3P
Molecular Weight	510.57 g/mol
Synonyms	(S)-Methyl 2-((1-(2-(diphenylphosphino)phenyl)-2-((p-tolyl)amino)-2-oxoethyl)amino)-3-methylbutanoate; L-Valine, N-[1-[2-(diphenylphosphino)phenyl]-2-[(4-methylphenyl)amino]-2-oxoethyl]-, methyl ester; Methyl (2S)-2-({1-[2-(diphenylphosphanyl)phenyl]-2-[(4-methylphenyl)amino]-2-oxoethyl}amino)-3-methylbutanoate; 500316-82-5; A chiral valine-phosphine hybrid ligand precursor
EINECS	Contact for details

Quality Control

Every batch of our L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-[(4-Methylphenyl)Amino]-2-Oxoethyl]-, Methyl Ester (9Ci) is produced under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques, including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container sealed to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.