Description

L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-(Methylamino)-2-Oxoethyl]-, Methyl Ester (9Ci) is a sophisticated chiral organophosphorus compound derived from the amino acid L-valine. This molecule is of significant interest due to its role as a key intermediate or ligand in advanced catalytic and synthetic organic chemistry processes. It is primarily sought by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and specialty materials where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex, biologically active molecules, particularly those requiring chiral phosphine ligands for asymmetric catalysis.
• Catalyst Ligand Development: Used in the research and development of novel transition metal catalysts for asymmetric hydrogenation, cross-coupling, and other stereoselective transformations.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents where specific chirality enhances efficacy and reduces environmental impact.
• Material Science: Potential application in the creation of chiral polymers or functionalized surfaces for sensor technology and separation science.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new reaction pathways in chemical discovery.

Basic Information

Product Name	L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-(Methylamino)-2-Oxoethyl]-, Methyl Ester (9Ci)
CAS No.	500316-81-4
Molecular Formula	C29H33N2O3P
Molecular Weight	488.56 g/mol
Synonyms	Methyl (2S)-2-[[(2R)-1-[2-(diphenylphosphanyl)phenyl]-2-(methylamino)-2-oxoethyl]amino]-3-methylbutanoate; L-Valine, N-[(1R)-1-[2-(diphenylphosphino)phenyl]-2-(methylamino)-2-oxoethyl]-, methyl ester; Chiral Valine-Derived Phosphine Amide Ester; Asymmetric Synthesis Ligand Intermediate; (R)-2-((S)-2-Methoxy-3-methyl-1-oxobutan-2-yl)(methyl)carbamoyl)-[1,1'-biphenyl]-2-yl)diphenylphosphine
EINECS	Contact for details

Quality Control

Every batch of L-Valine, n-[1-[2-(Diphenylphosphino)Phenyl]-2-(Methylamino)-2-Oxoethyl]-, Methyl Ester (9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere, such as argon or nitrogen, to prevent oxidation. Keep the container sealed to minimize exposure to moisture. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.