Description

3,4-Phospholanediol, 2,5-Dimethyl-1-Phenyl-, (2R,3R,4R,5R)- (9Ci) is a high-purity, stereochemically defined organophosphorus compound. This chiral phospholane diol serves as a critical building block and ligand precursor in advanced asymmetric synthesis, offering precise control over reaction stereochemistry. It is essential for research and development in pharmaceutical chemistry, agrochemicals, and specialty materials where enantioselectivity is paramount. Our supply ensures consistent quality and reliable availability for your most demanding synthetic applications.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of bidentate phosphine and phosphinite ligands used in asymmetric hydrogenation and other catalytic transformations.
• Pharmaceutical Intermediates: Enables the stereocontrolled synthesis of complex, bioactive molecules, including potential active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis: Employed in the development of novel catalytic systems for creating chiral centers with high enantiomeric excess (ee).
• Material Science: A building block for chiral polymers or frameworks with potential applications in sensors and separation technologies.
• Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in stereoselective organic synthesis.

Basic Information

Item	Details
Product Name	3,4-Phospholanediol, 2,5-Dimethyl-1-Phenyl-, (2R,3R,4R,5R)- (9Ci)
CAS No.	500000-20-4
Molecular Formula	C12H17O2P
Molecular Weight	224.24 g/mol
Synonyms	(2R,3R,4R,5R)-2,5-Dimethyl-1-phenyl-3,4-phospholanediol; (2R,3R,4R,5R)-1-Phenyl-2,5-dimethylphospholane-3,4-diol; (R,R,R,R)-1-Phenyl-2,5-dimethylphospholane-3,4-diol; (2R,3R,4R,5R)-1-Phenyl-2,5-dimethyl-1-phospha-3,4-cyclopentanediol; Chiral Phospholane Diol; Phenyl-Dimethylphospholanediol
EINECS	Contact for details

Quality Control

Every batch of 3,4-Phospholanediol, 2,5-Dimethyl-1-Phenyl-, (2R,3R,4R,5R)- (9Ci) is manufactured and tested under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.