Description

Acyclovir CAS NO 59877-89-3 is a synthetic nucleoside analogue and a potent antiviral agent. It is a critical active pharmaceutical ingredient (API) used to inhibit the replication of herpes viruses. This compound is essential for manufacturers in the pharmaceutical industry producing antiviral medications. Its high purity and consistent quality are paramount for ensuring the efficacy and safety of the final drug products.

Application

• As the active pharmaceutical ingredient (API) in antiviral creams, ointments, and topical formulations for the treatment of herpes simplex virus (HSV) skin infections.
• As the key component in oral tablet and capsule formulations for the systemic treatment of genital herpes, herpes zoster (shingles), and chickenpox.
• In the manufacture of intravenous (IV) solutions for the management of severe herpes virus infections in hospitalized patients.
• For use in ophthalmic preparations (eye ointments/gels) to treat herpes simplex keratitis.
• In research and development as a reference standard and for the synthesis of novel antiviral compounds.
• As a starting material or intermediate in the pharmaceutical synthesis of related nucleoside analogue prodrugs.

Basic Information

Product Name	Acyclovir
CAS No.	59877-89-3
Molecular Formula	C8H11N5O3
Molecular Weight	225.21 g/mol
Synonyms	Acycloguanosine; ACV; 9-[(2-Hydroxyethoxy)methyl]guanine; Zovirax (brand name); Aciherpin; Aciclovir; Acyclovirum; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
EINECS	261-960-5

Quality Control

Our Acyclovir is manufactured under strict quality management systems. It is tested to meet or exceed relevant pharmacopoeial standards such as USP, EP, and BP. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 6.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Microbial Limits	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.