Description

Cyclosporin C CAS NO 59787-61-0 is a naturally occurring cyclic undecapeptide and a structural analog of the well-known immunosuppressant Cyclosporin A. This compound is of significant interest in biochemical and pharmaceutical research for its distinct biological profile and its role in studying structure-activity relationships within the cyclosporin family. It serves as a critical reference standard and a key intermediate for researchers and developers in the life sciences sector. Primary demand originates from pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on immunology, pharmacology, and novel therapeutic discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in drug research and manufacturing.
• Biochemical Research: Essential for studying immunosuppressive mechanisms, structure-activity relationships (SAR), and the biological function of cyclosporin analogs.
• Drug Discovery & Development: Acts as a key intermediate or a lead compound in the synthesis and screening of novel immunosuppressive or anti-inflammatory agents.
• Academic & Institutional Research: Utilized in university and research institute laboratories for fundamental studies in immunology, cell biology, and medicinal chemistry.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the biotransformation of cyclosporin-based therapeutics.

Basic Information

Product Name	Cyclosporin C
CAS No.	59787-61-0
Molecular Formula	C₆₂H₁₁₁N₁₁O₁₂
Molecular Weight	1218.61 g/mol
Synonyms	Cyclosporin C; Ciclosporin C; [Thiomethyl-D-Ala]³-Ciclosporin; [Thiomethyl-D-Ala]³-Cyclosporin A; Cyclosporine C; UNII-0QZ6W8998S; 0QZ6W8998S; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
EINECS	Contact for details

Quality Control

Our Cyclosporin C is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided, documenting all critical quality attributes. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.