Description

Hemoglobin York CAS NO 59355-66-7 is a specific variant of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This compound is of significant interest for biochemical research and diagnostic development due to its unique structural characteristics. It serves as a critical reference material for scientists and manufacturers in the life sciences, pharmaceutical, and clinical diagnostics sectors.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for studying hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Reagent Manufacturing: A key component in the calibration and quality control of clinical analyzers and test kits for blood gas and hematology analysis.
• Pharmaceutical Development: Employed in research for blood substitute technologies and therapeutic agents targeting hemoglobinopathies.
• Academic & Clinical Studies: Essential for investigating specific hemoglobin variants, their physiological impact, and associated clinical conditions.
• Quality Control Material: Serves as a controlled substance for verifying the performance of laboratory instrumentation and analytical methods.

Basic Information

Product Name	Hemoglobin York
CAS No.	59355-66-7
Molecular Formula	C2952H4664N812O840S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb York; Hemoglobin Variant York; α-2 β-2(146 His->Pro); HBB: c.439C>A; Deoxyhemoglobin York; Oxyhemoglobin York; Methemoglobin York
EINECS	Contact for details

Quality Control

Our Hemoglobin York is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and stability, meeting the exacting standards required for research and in-vitro diagnostic use. Certificates of Analysis (COA) detailing purity, spectral data, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. Aliquot into single-use vials after thawing to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95% (Hemoglobin York)
Assay (Spectrophotometric)	≥ 90% functional hemoglobin
Methemoglobin Content	≤ 5%
Water Content (KF)	≤ 5.0%
Solubility	Clear solution in buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.