Description

Acyclovir CAS NO 59277-89-3 is a synthetic nucleoside analogue and a potent antiviral agent. It is a critical active pharmaceutical ingredient (API) used to inhibit the replication of herpes viruses. This compound is essential for manufacturers in the pharmaceutical industry producing antiviral medications for the treatment of infections such as herpes simplex, varicella zoster (chickenpox and shingles), and Epstein-Barr virus.

Application

• Pharmaceutical API: Primary use as the active ingredient in antiviral tablets, capsules, creams, and intravenous formulations.
• Generic Drug Manufacturing: Sourcing for the production of cost-effective generic antiviral medicines for global healthcare markets.
• Topical Antiviral Creams & Ointments: Used in the formulation of creams for the treatment of cold sores (herpes labialis) and genital herpes.
• Ophthalmic Preparations: Incorporated into eye ointments for the management of herpes simplex keratitis.
• Veterinary Pharmaceuticals: Application in antiviral treatments for veterinary use.
• Research & Development: Serves as a reference standard and key intermediate in virology research and the development of new antiviral therapies.

Basic Information

Product Name	Acyclovir
CAS No.	59277-89-3
Molecular Formula	C8H11N5O3
Molecular Weight	225.21 g/mol
Synonyms	Acycloguanosine; ACV; Zovirax (brand name); 9-[(2-Hydroxyethoxy)methyl]guanine; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; Aciherpin; Aciclovir; Acyclovirum
EINECS	261-685-1

Quality Control

Our Acyclovir is manufactured under strict quality management systems. We provide material that meets or exceeds major pharmacopoeial standards, including USP, EP, and BP monographs. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring compliance for GMP pharmaceutical production. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 6.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.