Description

β-D-Glucopyranosiduronic Acid, (3α,5β,7α,12α)-23-Carboxy-7,12-Dihydroxy-24-Norcholan-3-Yl, Disodium Salt (9Ci) is a high-purity, conjugated bile acid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound matters as a critical reference standard and synthetic intermediate for investigating metabolic pathways, drug metabolism, and bile acid receptor activity. It is primarily needed by research institutions and pharmaceutical companies engaged in hepatology, gastroenterology, and metabolic disorder studies.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quality control and analytical method development of bile acid-based pharmaceuticals.
• Biochemical Research: Serves as a key substrate or inhibitor in enzymatic studies related to bile acid synthesis and conjugation pathways.
• Metabolite Synthesis: Acts as a crucial synthetic intermediate for the preparation of novel bile acid metabolites and analogs for biological screening.
• Diagnostic Reagent Development: Employed in the formulation of calibration kits and reagents for clinical diagnostics targeting liver function and bile acid profiles.
• Cell Culture & In Vitro Studies: Utilized in cell-based assays to study the effects of conjugated bile acids on hepatocyte function and Farnesoid X Receptor (FXR) signaling.

Basic Information

Product Name	β-D-Glucopyranosiduronic Acid, (3α,5β,7α,12α)-23-Carboxy-7,12-Dihydroxy-24-Norcholan-3-Yl, Disodium Salt (9Ci)
CAS No.	59274-69-0
Molecular Formula	C31H48Na2O12
Molecular Weight	658.70 g/mol
Synonyms	Disodium Taurochenodeoxycholate 3-Sulfate; 3α,7α-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)-amide Disodium Salt; Taurochenodeoxycholic Acid Sulfate Disodium Salt; TCDCA-SO4 Na2; Chenodeoxycholyltaurine Sulfate Disodium Salt; (3α,5β,7α)-3,7-Dihydroxy-24-[[(2-sulfoethyl)amino]carbonyl]cholan-24-oate Disodium Salt; 7α-Hydroxytaurochenodeoxycholic Acid Sulfate Disodium Salt
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranosiduronic Acid, (3α,5β,7α,12α)-23-Carboxy-7,12-Dihydroxy-24-Norcholan-3-Yl, Disodium Salt (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent moisture absorption and degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.