Description

Decarbamylsaxitoxin is a potent neurotoxin and a key structural analog of saxitoxin, a compound of significant scientific and pharmacological interest. Its primary value lies in its use as a critical reference standard and research tool for studying sodium channel blockers and paralytic shellfish poisoning (PSP) toxins. This high-purity compound is essential for researchers and quality control laboratories in the fields of marine toxin analysis, neuroscience, pharmacology, and food safety testing.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the accurate quantification of saxitoxin and its analogs in complex matrices.
• Marine Biotoxin Research: Critical for studying the metabolism, toxicology, and environmental impact of paralytic shellfish poisoning (PSP) toxins.
• Neuroscience & Pharmacology: Used as a selective sodium channel (NaV) blocker to investigate ion channel function, nerve signal transmission, and potential therapeutic applications.
• Food Safety & Regulatory Testing: Employed in the development and validation of analytical methods (e.g., HPLC, LC-MS/MS) to monitor shellfish and seafood for regulatory compliance.
• Toxicology Studies: Serves as a model compound for assessing toxicity, understanding structure-activity relationships (SAR) within the saxitoxin family, and developing detection assays.
• Diagnostic Development: Used in the production of antibodies and the calibration of biosensors or immunoassay kits for rapid toxin detection.

Basic Information

Product Name	Decarbamylsaxitoxin
CAS No.	58911-04-9
Molecular Formula	C9H15N7O4
Molecular Weight	285.26 g/mol
Synonyms	Decarbamoylsaxitoxin; De-Carbamoyl Saxitoxin; GTX-5; GTX5; 11-Hydroxysaxitoxin; Saxitoxin Decarbamoyl Analog; STX-dc; 1,2,3,7,8,9-Hexahydro-2,6-diamino-8-hydroxy-7-methylpurinium-8,9-diol
EINECS	Contact for details

Quality Control

Our Decarbamylsaxitoxin is produced under strict quality management protocols to ensure the highest standards of purity and consistency required for research and analytical applications. Each batch is characterized using advanced analytical techniques including HPLC, LC-MS/MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.