Description

24-Hydroxyvitamin D2 is a key hydroxylated metabolite of ergocalciferol (Vitamin D2), playing a significant role in calcium homeostasis and bone metabolism research. This compound is essential for scientists and manufacturers developing analytical standards, diagnostic reagents, and advanced pharmaceutical intermediates. It is particularly valuable for research institutions and companies in the pharmaceutical, nutraceutical, and clinical diagnostics sectors focused on Vitamin D metabolism and related endocrine pathways.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quantitative analysis of Vitamin D2 metabolites in drug formulations and biological samples.
• Clinical Diagnostics: Serves as a critical calibrator and control in LC-MS/MS and HPLC assays for accurately measuring 24-Hydroxyvitamin D2 levels in human serum, supporting metabolic disorder studies.
• Biochemical Research: A vital tool for in vitro and in vivo studies investigating the catabolic pathways, biological activity, and regulatory functions of Vitamin D2 metabolites.
• Nutraceutical Development: Employed in the research and quality control of advanced Vitamin D supplements and fortified foods to understand metabolic profiles.
• Metabolite Synthesis: Acts as a key intermediate in the organic synthesis of further modified Vitamin D2 analogs for therapeutic exploration.

Basic Information

Product Name	24-Hydroxyvitamin D2
CAS No.	58050-56-9
Molecular Formula	C28H44O3
Molecular Weight	428.65 g/mol
Synonyms	24-Hydroxyergocalciferol; 24(OH)D2; (3β,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-3,24-diol; 24-Hydroxycalciferol; Vitamin D2 24-hydroxylated metabolite; 24-Hydroxy vitamin D2
EINECS	Contact for details

Quality Control

Our 24-Hydroxyvitamin D2 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the container in a freezer at -20°C or below. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.