Description

Voxilaprevir is a direct-acting antiviral agent (DAA) specifically designed as an NS3/4A protease inhibitor. This compound is a critical active pharmaceutical ingredient (API) in the fight against chronic hepatitis C virus (HCV) infection, offering a targeted mechanism of action. It is essential for pharmaceutical manufacturers and research institutions developing and producing next-generation antiviral therapies. The product is supplied under the identifier CAS NO 57818-44-7.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in fixed-dose combination antiviral medications.
• Key component in Hepatitis C Virus (HCV) treatment regimens, particularly for genotype 1-6 infections.
• Critical material for pharmaceutical R&D focused on novel antiviral drug development and combination therapies.
• Reference standard for analytical method development and quality control testing in QC/QA laboratories.
• Used in preclinical and clinical studies to evaluate pharmacokinetics and efficacy.
• Starting material or intermediate for the synthesis of related pharmaceutical compounds.

Basic Information

Product Name	Voxilaprevir
CAS No.	57818-44-7
Molecular Formula	C₄₀H₅₀N₆O₉S
Molecular Weight	766.93 g/mol
Synonyms	Voxilaprevir; GS-9857; (1R,18R,20R,24S,27S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[[5-methyl-6-(2-methyl-3-pyridinyl)-2-pyridinyl]carbonyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-20,24-bis(1-methylethyl)-8,11,14,17,22-pentaoxo-18-(phenylmethyl)-3,6-dioxa-9,12,15,16,21-pentaazatetracosane-1,27-dicarboxamide; GS9857
EINECS	Contact for details

Quality Control

Our Voxilaprevir is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory compliance and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	<20 ppm
Water Content (KF)	<1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.