Description

(1S,2S)-trans-1,2-Cyclohexanediol is a high-purity chiral diol building block essential for asymmetric synthesis and pharmaceutical intermediate manufacturing. Its rigid, defined stereochemistry provides a critical scaffold for constructing complex molecules with precise three-dimensional orientation. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for active pharmaceutical ingredients (APIs), ligands, and chiral auxiliaries.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drugs and bioactive molecules.
• Chiral Ligand & Catalyst Synthesis: Used to construct sophisticated ligands for asymmetric catalysis, including hydrogenation and oxidation reactions.
• Agrochemical Active Ingredients: Serves as a building block for chiral herbicides, fungicides, and plant growth regulators.
• Polymer & Resin Modifier: Imparts rigidity and specific stereochemistry into specialty polymers and epoxy resin systems.
• Flavor & Fragrance Chemistry: Employed in the synthesis of stereodefined aroma chemicals and natural product analogs.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(1S,2S)-trans-1,2-Cyclohexanediol
CAS No.	57794-08-8
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(1S,2S)-1,2-Dihydroxycyclohexane; (1S,2S)-Cyclohexane-1,2-diol; trans-(1S,2S)-1,2-Cyclohexanediol; (1S,2S)-CHD; (-)-trans-1,2-Cyclohexanediol; (1S,2S)-1,2-Cyclohexyleneglycol; L-(+)-trans-1,2-Cyclohexanediol (obsolete naming)
EINECS	Contact for details

Quality Control

Our (1S,2S)-trans-1,2-Cyclohexanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for enantiomeric excess and chemical purity. Certificates of Analysis (COA) with full chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP intermediate requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.