Description

(R)-(+)-Glycidol is the single enantiomer of glycidol, a versatile chiral epoxide and a crucial building block in asymmetric synthesis. Its high optical purity makes it indispensable for creating enantiomerically pure pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, fine chemical, and specialty polymer industries who require precise stereochemical control in their synthetic pathways.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for active pharmaceutical ingredients (APIs) requiring specific (R)-configuration, such as β-blockers and other cardiovascular drugs.
• Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and reduced environmental impact.
• Fine Chemical and Specialty Polymer Building Block: Employed to introduce chiral glycidyl ether or alcohol functionalities into complex molecules, liquid crystals, and advanced polymeric materials.
• Bioconjugation and Linker Chemistry: Utilized for modifying biomolecules, proteins, and peptides due to its reactivity with nucleophiles like amines and thiols under mild conditions.
• Asymmetric Catalyst and Ligand Synthesis: Serves as a starting material for preparing chiral catalysts and ligands used in enantioselective transformations.
• Research & Development: A valuable tool for academic and industrial R&D in organic chemistry and medicinal chemistry for exploring new chiral synthetic routes.

Basic Information

Product Name	(R)-(+)-Glycidol
CAS No.	57044-25-4
Molecular Formula	C3H6O2
Molecular Weight	74.08 g/mol
Synonyms	(R)-(+)-Glycidol; (R)-Glycidol; (+)-(R)-Glycidol; (R)-2,3-Epoxy-1-propanol; (R)-Oxiranemethanol; (R)-(-)-2,3-Epoxypropan-1-ol (enantiomer); (R)-1,2-Epoxy-3-hydroxypropane; (R)-3-Hydroxy-1,2-epoxypropane
EINECS	Contact for details

Quality Control

Our (R)-(+)-Glycidol is produced under strict quality management systems to ensure batch-to-batch consistency and high optical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.