Description

4-Amino-1-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-2(1H)-Pyrimidinone is a fluorinated nucleoside analog, a key building block in medicinal chemistry and pharmaceutical research. This compound is valued for its role as a critical intermediate in the synthesis of antiviral and anticancer agents, particularly those targeting viral polymerases. It is essential for researchers and manufacturers in the pharmaceutical industry developing novel therapeutics, as well as for academic institutions conducting advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antiviral drugs, including nucleoside reverse transcriptase inhibitors.
• Anticancer Agent Research: Serves as a building block for developing novel chemotherapeutic compounds that interfere with DNA synthesis.
• Biochemical Research: Used in enzymatic studies and as a substrate or inhibitor to investigate polymerase mechanisms.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance bioavailability and targeting.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Antiviral Screening: Acts as a core structure for screening libraries against a range of viral targets.

Basic Information

Product Name	4-Amino-1-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-2(1H)-Pyrimidinone
CAS No.	56632-83-8
Molecular Formula	C9H12FN3O4
Molecular Weight	245.21 g/mol
Synonyms	2'-Fluoro-2'-deoxyarabinofuranosylcytosine; 2'-F-ara-C; 2'-Fluoro-arabinofuranosylcytosine; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine; β-2'-Fluoro-2'-deoxyarabinofuranosylcytosine; FAraC; 2'-Fluoro-2'-deoxy-1-β-D-arabinofuranosylcytosine; 2'-F-Arabinofuranosylcytosine
EINECS	Contact for details

Quality Control

Our 4-Amino-1-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-2(1H)-Pyrimidinone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory standards (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.