Description

Acetophenone, [Methyl-14C] is a carbon-14 radiolabeled analog of acetophenone, a key aromatic ketone. This isotopically labeled compound is essential for conducting precise metabolic and environmental fate studies, providing critical data on molecular pathways and degradation. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and environmental science sectors for advanced analytical applications such as tracer studies and pharmacokinetic research.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in pharmaceutical research to study the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and related compounds.
• Environmental Fate Studies: Applied in agrochemical and environmental research to track the degradation, transformation, and persistence of chemical entities in ecosystems.
• Biochemical Research: Serves as a tool in mechanistic studies to elucidate reaction pathways and intermediate formation in organic and biochemical synthesis.
• Analytical Method Development: Employed as an internal standard or reference material in advanced chromatographic (e.g., LC-MS) and spectroscopic analytical techniques.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of potential genotoxic impurities or metabolites in active pharmaceutical ingredient (API) development.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex radiolabeled molecules for research purposes.

Basic Information

Product Name	Acetophenone, [Methyl-14C]
CAS No.	56624-91-0
Molecular Formula	C₈H₈O (with ¹⁴C label on the methyl group)
Molecular Weight	~120.15 g/mol (exact mass depends on specific activity)
Synonyms	1-Phenylethanone-1-¹⁴C; Methyl phenyl ketone-¹⁴C; Phenyl methyl ketone-¹⁴C; ¹⁴C-Acetophenone; Radiola beled Acetophenone; [Methyl-¹⁴C]Acetophenone; Acetophenone (methyl-¹⁴C); NSC 7636-¹⁴C
EINECS	Contact for details

Quality Control

Every batch of Acetophenone, [Methyl-14C] is manufactured and analyzed under strict quality systems to ensure traceability, purity, and specific activity. Certificates of Analysis (COA) are provided, detailing key parameters such as radiochemical purity, chemical purity, specific activity, and solvent composition. Our quality commitment aligns with the standards required for research chemicals in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures, typically 2-8°C or as specified on the label. Due to its highly volatile nature, ensure containers are securely sealed and stored in a well-ventilated area designated for radiochemicals. Follow all local and international regulations for the handling and storage of radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC / HPLC)	≥ 98%
Specific Activity	Customizable (mCi/mmol)
Solvent	Specified (e.g., Toluene, Ethanol)
Concentration	Specified (mCi/mL or mg/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.