Description

(R)-Viloxazine Hydrochloride CAS NO 56287-63-9 is the single enantiomer form of the norepinephrine reuptake inhibitor viloxazine. This high-purity chiral intermediate is critical for the research and development of enantiomerically pure pharmaceuticals, where the specific stereochemistry can significantly impact biological activity and safety profiles. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel central nervous system (CNS) therapeutics and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical and clinical research for studying norepinephrine reuptake inhibition and developing treatments for CNS disorders.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in the development and scale-up of asymmetric synthesis routes for complex molecules.
• Metabolite Studies: Utilized in the synthesis and identification of drug metabolites for pharmacokinetic and safety evaluations.

Basic Information

Product Name	(R)-Viloxazine Hydrochloride
CAS No.	56287-63-9
Molecular Formula	C13H19NO2·HCl
Molecular Weight	257.76 g/mol (as hydrochloride salt)
Synonyms	(R)-2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride; (R)-Viloxazine HCl; (R)-Viloxazine monohydrochloride; (R)-Vivalan hydrochloride; (R)-Viloxazine hydrochloride enantiomer; (R)-Enantiomer of Viloxazine HCl; (R)-EMD-31,742
EINECS	Contact for details

Quality Control

Our (R)-Viloxazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data, including enantiomeric excess (ee), are provided to guarantee reproducible quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.