Description

2-(3,4-Dichlorophenyl)-2,2-Difluoroacetic Acid is a high-purity, halogenated acetic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique difluoroacetic acid moiety attached to a dichlorinated phenyl ring makes it a valuable intermediate for creating compounds with tailored biological and physical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce specific halogenated motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluoro and dichloro groups contribute to enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, including fluorinated polyesters and polyamides with unique surface properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	2-(3,4-Dichlorophenyl)-2,2-Difluoroacetic Acid
CAS No.	56072-00-5
Molecular Formula	C8H4Cl2F2O2
Molecular Weight	241.02 g/mol
Synonyms	2,2-Difluoro-2-(3,4-dichlorophenyl)acetic Acid; (3,4-Dichlorophenyl)difluoroacetic Acid; α,α-Difluoro-3,4-dichlorophenylacetic Acid; 2-(3,4-Dichlorophenyl)-2,2-difluoroethanoic Acid; NSC 403796; Difluoro(3,4-dichlorophenyl)acetic Acid
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichlorophenyl)-2,2-Difluoroacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of our global B2B clients. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.