Description

1,3-Dioxolane-4,5-Dimethanol, 2,2-Dimethyl-, (4R,5S)-Rel- is a high-value chiral building block and intermediate in fine chemical synthesis. This compound matters for its role in constructing complex molecular architectures with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to produce enantiomerically pure compounds. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and purity for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular research.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of complex, naturally-derived odorants and flavoring agents.

Basic Information

Product Name	1,3-Dioxolane-4,5-Dimethanol, 2,2-Dimethyl-, (4R,5S)-Rel-
CAS No.	55904-12-6
Molecular Formula	C7H14O4
Molecular Weight	162.18 g/mol
Synonyms	(4R,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; (rel)-(4R,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; 2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol, (4R,5S)-rel-; (4R,5S)-rel-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; (R*,S*)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; Isosorbide derivative; Chiral dioxolane dimethanol
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4,5-Dimethanol, 2,2-Dimethyl-, (4R,5S)-Rel- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure compliance with customer specifications and internal standards for identity, purity, and chiral integrity. Certificates of Analysis (COA) documenting key parameters such as assay, enantiomeric excess, and impurity profiles are available upon request. We support cGMP manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.