Description

Ethyl 4-(1,1-Difluoroethyl)Benzoate is a high-purity fluorinated aromatic ester building block, valued for its role in introducing the difluoroethyl group into complex molecular architectures. This compound is essential for researchers and manufacturers requiring precise fluorination to modulate the physicochemical properties of target molecules. It is primarily utilized in the development of advanced pharmaceuticals, agrochemicals, and specialty materials where fluorine substitution is critical for enhancing bioavailability, stability, or activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for introducing lipophilic and metabolically stable difluoroethyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluoroethyl group can improve pesticidal efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic displays and optoelectronic devices.
• Polymer & Resin Modifier: Incorporated to develop specialty polymers with enhanced chemical resistance, lower dielectric constants, or altered surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and other transformations in medicinal and process chemistry R&D.
• Fluorine-19 NMR Reagent: Potentially useful as a standard or probe in magnetic resonance imaging (MRI) agent research due to the fluorine atoms.

Basic Information

Product Name	Ethyl 4-(1,1-Difluoroethyl)Benzoate
CAS No.	55805-23-7
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	Benzoic acid, 4-(1,1-difluoroethyl)-, ethyl ester; Ethyl 4-(1,1-difluoroethyl)benzoate; 4-(1,1-Difluoroethyl)benzoic acid ethyl ester; Ethyl p-(1,1-difluoroethyl)benzoate; 55805-23-7; Ethyl 4-(α,α-difluoroethyl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(1,1-Difluoroethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.