Description

3-Carboxy-Alpha,α-Difluorotoluene, also known as 3-Carboxybenzal Fluoride, is a versatile difluorinated aromatic building block. This compound is valued for its unique chemical structure, which introduces both a carboxylic acid group and a difluoromethyl moiety onto a benzene ring, enabling precise molecular modifications. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring the difluoromethyl group for metabolic stability or bioavailability enhancement.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoromethyl motif can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Advanced Polymer Modification: Employed to introduce fluorine and carboxylic acid functionality into polymer chains, altering surface properties, chemical resistance, and adhesion.
• Organic Synthesis & Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex, fluorinated molecules in medicinal and materials chemistry.

Basic Information

Product Name	3-Carboxy-Alpha,α-Difluorotoluene / 3-Carboxybenzal Fluoride
CAS No.	55805-20-4
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	3-(Difluoromethyl)benzoic acid; α,α-Difluoro-m-toluic acid; 3-(Difluoromethyl)benzenecarboxylic acid; Benzoic acid, 3-(difluoromethyl)-; m-(Difluoromethyl)benzoic acid; 3-Carboxybenzal difluoride; 3-Carboxy-α,α-difluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Carboxy-Alpha,α-Difluorotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.